Postdoctoral Fellow - Discovering Novel Genetic and Epigenetic Regulations - Jianjun Chen Laboratory
Thanks for your interest in the Postdoctoral Fellow - Discovering Novel Genetic and Epigenetic Regulations - Jianjun Chen Laboratory position.
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Basic education, experience and skills required for consideration:
- The candidates for the Postdoctoral scientist position should have a Ph.D. and/or M.D. degree(s), and a solid background in biochemistry, mouse model studies, hematology, epigenetics, immunology, pathology, and/or stem cell research.
- The candidates should not have more than three years of postdoc training experience.
- The candidates should be highly motivated individuals with the ability to work in a team environment and with good oral and written communication skills in English.
Additional Information:
Your application, including CV, brief motivation statement, and contact information of three scientific mentors (references), should be saved as a single PDF. The PDF file can be sent to Dr. Jianjun Chen (jianchen@coh.org) directly.
Examples of recent work:
- Jiang X, Huang H, Li Z (…) & Chen J. Blockade of miR-150 maturation by MLLfusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell. 22: 524-535.(2012)
- Li Z, Herold T, He C (…) & Chen J. Identification of a 24-Gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: An International Collaborative Study of 1,324 Patients. Journal of Clinical Oncology. 31(9):1172-81. (2013)
- Jiang X, Hu C, Arnovitz S (…) & Chen J. miR-22 has a potent anti-tumor role with therapeutic potential in acute myeloid leukemia. Nature Communications. 7:11452. (2016)
- Li Z, Weng H, Su R, (…) & Chen J. FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. Cancer Cell. 31(1):127-141.(2017)
- Jiang X, Hu C, Ferchen K (…) & Chen J. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. Nature Communications. 8:2099.(2017)
- Su R, Dong L, Li C (…) & Chen J. R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling. Cell. 172(1-2):90-105. (2018)
- Weng H, Huang H, Wu H (…) & Chen J. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 22(2):191-205. (2018)
- Huang H, Weng H, Sun W, (…) Chen J. Recognition of RNA N6-methyadenosine by IGF2BP proteins Enhances mRNA Stability and Translation. Nature Cell Biology. 20(3):285-295. (2018)
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
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