Postdoctoral Fellow - Protein Engineering - Williams Lab
Basic education, experience and skills required for consideration:
- PhD in chemistry, biochemistry, protein chemistry, biochemical engineering or related field with 1 to 3 years of postdoctoral experience
- Experience with protein expression and purification
- Fully versed in protein purification methods (Affinity, SEC, IEX), analysis (e.g., SDS-PAGE)
- Experience with cell culture (E. coli and CHO a must, yeast and insect desirable). Experience with SPR and other biophysical methods desirable
- Protein engineering, production, purification in CHO
- Biophysical characterization (SPR, ITC, AUC, CD)
- X-ray Crystallography
- Assay development, interpretation, and troubleshooting
- Excellent written and verbal communication skills
- Good problem solving skills
- Ability to conduct independent research
- Ability to supervise others and work effectively in a team
Preferred education, experience and skills:
- Enzymology experience a plus
- CryoEM experience a plus
City of Hope is a world leader in translational medicine, including synthesis of first synthetic gene, humanization of monoclonal antibodies and pioneering work in CAR T cells. These discoveries have led to some of the most important therapeutics in world including recombinant insulin for maintenance of type 2 diabetes and Rituxan, Herceptin, Avastin, etc. for the treatment of cancer. Building off these successes, City of Hope houses three FDA approved GMP facilities along with its 27 core facilities to rapidly advance discoveries.
- For more information about Dr. Williams' research, please click here.
- Please note, this is one of three Postdoctoral Fellowships available in Dr. Williams' lab.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
