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Project Development Scientist (Staff Scientist) Immunotherapy Center

10001693 Requisition #
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About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.  Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
This Project Development Scientist position will be part of the established Clinical and Translational Project Development Core of the Hematologic Malignancies and Stem Cell Transplantation Institute (Heme Institute). This Core supports project management, scientific writing and clinical trial design for the seven focus centers within the Heme Institute. This Project Development Scientist will be affiliated with the Immunotherapy Center led by Drs. Stephen Forman and Christine Brown, focusing on tumor-specific chimeric antigen receptor (CAR) T cell translational research. S/he will work closely with the Immunotherapy Center-associated laboratory and clinical researchers, regulatory staff and biostatisticians to shepherd projects from conception to grant submission, to clinical protocol, to manuscript.

Key Responsibilities include:

  • Develop In-depth Knowledge of Immunotherapy Center Research Goals and Areas of Emphasis: Scientists are expected to become well-versed in the terminology, biology and treatments associated with the Immunotherapy Center. Scientists will attend Immunotherapy Center Leadership meetings, Disease Team meetings, pre-clinical research data meetings, and relevant seminars and conferences to gain a thorough familiarity with the ongoing research interests of the Immunotherapy Center.
  • Project Design and Grant Writing: Scientists will assist and advise Immunotherapy Center senior researchers in design and preparation of new projects for funding as well as managing the logistics of grant submission. They will help match investigators to appropriate grant opportunities throughout the stages of project and career development. They will edit/write portions of the grant text and frame the project as appropriate for the specific application. They will also assist in preparing grant progress reports for grants that have been awarded.
  • Clinical Protocol Writing and Submission: Scientists will work with the protocol design team (laboratory and clinical investigators, biostatisticians, research nurses, investigational pharmacists) on clinical trial design and protocol preparation for Immunotherapy Center investigator-initiated early-phase clinical trials. Scientists will interface with Research Support Services to develop consent forms. For translational projects involving a City of Hope-held Investigational New Drug Application (IND), they will provide and review text and figures for IND submission.
  • Manuscript Writing and Public Access Compliance: Scientists will advise and assist Immunotherapy Center investigators with interpretation and presentation of data for publication, and selection of appropriate journals for submission. They will edit/write portions of the manuscript text. They will also ensure that the appropriate funding agencies and the City of Hope Comprehensive Cancer Center Support Grant are acknowledged, and that NIH-funded manuscripts are archived in PubMed Central.
  • Data Presentations: Scientists will work with investigators to assure the clarity and accuracy of data presented, as well as the interpretation of results. They will contribute to the aesthetic aspects of data presentation, including formatting of text (to required specifications) and creation/refinement of clear, appealing data figures, graphics and treatment schemas. This extends to meeting presentations, grants, protocols and manuscripts.

Keywords:  Project Management, Scientific Writing, Translational Research, CAR T cells.

Basic education, experience and skills required for consideration:

  • College degree in biological/chemical sciences.
  • Skills: Excellent scientific writing, organizational and interpersonal skills are key.
  • Aptitude: Ability to work independently and as part of a team, meet deadlines, perform and prioritize multiple simultaneous tasks.
  • Requires judgment that could affect the image of City of Hope and the Institute.
  • Software: Proficiency in use of Microsoft Word, EndNote, Excel and PowerPoint.
  • Communication: Strong written and verbal English is required.

Preferred education experience and skills:

  • Preferred PhD in the biological/chemical sciences; or, a master’s degree with at least five years or bachelor’s with 10 years, of scientific writing, clinical study design, or clinical trial regulatory experience in a healthcare/research/academic environment.
  • NIH or DOD research grant writing (R01 level, not post-doctoral fellowships), involvement with human observational or therapeutic studies, protocol design/writing for human sample, observational/retrospective or therapeutic studies. Familiarity with data analysis techniques, graphing methods, and interpretation of laboratory and clinical data.
  • Prefer familiarity with Adobe Acrobat and Illustrator.
    Working / Environmental Conditions: Subject to irregular hours, changing priorities and unpredictable situations; candidate must be able to handle stressful conditions while maintaining a high quality of workmanship and a professional demeanor.
    Physical Demands: Potential eye, back, neck and wrist fatigue due to extended time on the computer

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national  

origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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